Estrogen
Replacement
Therapy

Hormone Replacement Therapy Alternatives
Hot flashes, vaginal dryness, and mood swings are often experienced in menopausal women that were combated with hormone replacement therapy. Now women are wondering about hormone replacement therapy alternatives to treat their menopausal symptoms without taking the risk of developing breast cancer heart disease, stroke, or blood clots.

Click here to read more about hormone replacement therapy alternatives.

Previous Hormone Replacement Therapy Studies Inefficient

The largest study performed on hormone replacement therapy prior to the Women's Health Initiative study was at the end of the 1970s by the National Institute on Aging that did not have one woman in it. It was not until pressure from women's groups and congresswomen that the 1991 Women's Health Initiative hormone replacement therapy study was launched in order to gain insight to the ongoing debate on whether or not hormones were beneficial or harmful to women. The study was terminated early, after just five years, because the researchers found it unethical to the over 16,000 women participating due to the number of risks associated to hormone replacement therapy.

 

BREAST CANCER RISK ASSOCIATED WITH HORMONE REPLACEMENT THERAPY

In 1991, the National Institutes of Health began the first and only large study comparing the effects of hormone replacement therapy with placebos in healthy women. In July 2002, when researchers concluded that the drugs estrogen and progestin found in hormone replacement therapy had risks that clearly outweighed the benefits, the study was halted.The study was supposed to last until 2005, but was abruptly stopped when instances of heart attack, stroke, and breast cancer risk was associated with hormone replacement therapy. The 16,000 women participating in the hormone replacement therapy study were immediately sent letters instructing them to discontinue the use of the estrogen-progestin combination drug Prempro.

For many women, beginning menopause usually meant beginning hormone replacement therapy, the combination of estrogen and progestin that was believed to reduce the symptoms of menopause and promote general well being. Hormone replacement therapy has been prescribed as a common treatment for women who had not had a hysterectomy for decades now, with over 70 million prescriptions written for it every year. About 38% of women post-menopausal have been estimated to be using hormone replacement therapy.

Most women will have no problem stopping hormone replacement therapy or have any reason to continue taking them for the minimal symptoms they experience with menopause. The study results led many to question how one of the most commonly prescribed drugs had no previous studies performed indicating the serious health risks associated to the hormone replacement therapy. Medical experts, prior to the study's results, encouraged doctors to recommend almost every woman to use hormone replacement therapy when menopausal for general well being. Wyeth's Prempro, the top-selling drug for hormone replacement therapy and their related product Premphase, generated more than $2 billion in sales last year, and another estrogen replacement therapy Premarin sales were $1.3 billion last year.

Hormone Replacement Therapy: Once Fountain of Youth Now Risk Factor

For decades, women have been encouraged to use hormone replacement therapy when reaching menopause. Six million American women had been taking hormone replacement therapy before the announcement that serious hormone replacement therapy side effects can occur. The study's hormone replacement therapy findings were scheduled to be published in the July 17, 2002 Journal of the America Medical Association but were released early because the impact the estrogen-progestin combination could have on the high number of women prescribed one of the most common hormone replacment therapy treatments.

About the WHI Hormone
Replacement Therapy Study

From the start, a safety board was to monitor the data of the WHI, Women's Health Initiative, hormone replacement therapy study in order to ensure the study be stopped prior to 2005 if evidence showed the risks of hormone replacement therapy obviously outweighed the benefits. In late 1999, the monitoring board had seen an unexpected increase in risk of blood clots and heart attacks in the group of women taking hormone replacement therapy. The results were shocking because most doctors were under the impression that hormone replacement therapy protected against cardiovascular disease.

While this evidence became available, the hormone replacement therapy study still continued based on the reasoning that cardiovascular benefits may take longer to appear. By spring 2002, the likelihood of heart attacks and blood clots in the lungs and legs were present, but also an increased risk of breast cancer surfaced for those taking hormone replacement therapy. It was after that finding that the hormone replacement therapy study was terminated, leaving many women feeling "mystified and confused".

To obtain more information on your legal rights contact us to confer with a hormone replacement therapy attorney.


Estrogen Replacement Therapy Safe?

Although only one part of the study was halted for hormone replacement therapy, the other part is still continuing on estrogen taken alone. The researchers for the Women's Health Initiative study have not yet evaluated the benefits and risks of taking estrogen alone, so a second clinical trial of 11,000 women is being performed. However, women should remain wary of any drug that has no scientific evidence showing the long-term effects it can have on an individual's health. Even though estrogen showed it improves a woman's cholesterol many women with normal, healthy cholesterol levels still experience heart attacks.

The hormone replacement therapy study findings were so surprising to doctors that had gotten used to the common prescription that they had not realized how little amount of evidence existed. The hormone replacement therapy study was the first and only large study comparing the effects of hormone replacement therapy with placebos in healthy women. Wyeth Pharmaceutical's estrogen replacement therapy, Premarin had sales of $1.3 billion last year.


About Hormone Replacement Therapy

The hormone replacement therapy drugs, estrogen and progestin, have also been shown to not defy age as was previously thought . . . read more

Hormone Replacement Therapy Lawsuit

Wyeth, maker of the number one selling hormone replacement therapy Prempro, has experienced a 24% stock tumble after news that the large hormone replacement therapy study was halted because of the risk of heart disease, breast cancer, strokes, and blood clots found in healthy women on the estrogen/progestin combination . . . read more

Hormone Replacement Therapy Side Effects

Many people are questioning why it took so long for the hormone replacement therapy side effects to be discovered after millions of women had been using the commonly prescribed hormone treatment . . . read more

Hormone Replacement Therapy News

BREAKING NEWS!! October 2, 2003
"Ovarian risk amongst combined Hormone Replacement Therapy users"
Women taking estrogen plus progestin were diagnosed as having invasive ovarian cancer at a rate of 42 per 100,000 person-years in comparison to the 15 per 100,000 person-years in the placebo group. Read More..

BREAKING NEWS!! September 2003
"New Zealand Health Ministry to decide on Hormone Replacement Therapy"
Used by millions of women worldwide, recent research has shown that Hormone Replacement Therapy may increase risks of suffering breast cancer, strokes, blood clots, heart disease, and dementia. Read More...

More Hormone Replacement Therapy News...

Hormone Replacement Therapy Alternatives

Hormone replacement therapy had become such a common prescription that every year 70 million prescriptions were written for hormone replacement therapy that doctors encouraged almost every woman that had not had a hysterectomy to use when beginning menopause . . . read all the replacement alternatives

 

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